Sentinel Flea and Heartworm Preventive

SENTINEL® is the only once-a-month heartworm and flea preventative with the active ingredients of Lufenuron (PROGRAM®) and Milbemycin Oxime (INTERCEPTOR®).

SENTINEL is given on the same calendar day each month, with a complete meal. It can be crushed up or mixed with the dog's food as long as you are sure the dog eats the entire meal at one sitting.

Lufenuron works by preventing the linking of a chain of molecules in the flea called Chitin (KI-TIN). Chitin makes up the hard shell of the adult flea, as well as an egg-tooth that flea larve use to break out of their eggs. Without chitin these stages cannot develop properly and the life cycle is broken. Lufenuron is stored in the pet's body fat and released over the course of 32 days following dosing.

Milbemycin Oxime interferes with the nerve signal transmission of the L3 and L4 stages (called microfilariae) of the heartworm life cycle, killing them before they develop into adult heartworm. These are the stages present for 50-70 days after the dog has been bitten by an infective mosquito. Milbemycin Oxime also treats and controls adult intestinal parasites such as hookworm, whipworm and two types of roundworm.

SENTINEL is 100% absorbed 3 hours after the first dose, killing infective microfilarie, and interrupting the adult flea life cycle at the egg and larval stage. It is cleared from the pet's system in about 2 days. Worms may be seen in the dog's stool as early as the following day, and the effect on the adult fleas is seen as soon as they begin laying eggs.

SENTINEL does not kill adult fleas, so you may not immediately see how effective it is, but rest assured that adults currently on your pet will die off without reproducing. If you wish to take a more aggressive approach to killing the adults VIP PETCARE recommends treating your pet with ADVANTAGE or FRONTLINE adulticide in conjunction with SENTINEL.

SENTINEL has been tested and found safe for all breeds of dog including pregnant and nursing females, breeding males and puppies as young as 2 weeks of age and greater than 1kg in body weight.
Prescription Only

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